Xiao-Yu Teng
Postdoctoral Research Fellow
Email：tengxy@@gdiist.cn
Research Interests:
Nerve signal transmission and nervous system diseases.
Biography：
Xiao-Yu Teng received his Ph.D. degree from Nanjing University in 2021. From April 2022 to April 2025, he conducted postdoctoral research at the Guangdong Institute of Intelligence Science and Technology. Since May 2025, he has been serving as an associate researcher at the same institute. Dr. Teng has received numerous honors, including the National Scholarship and the Outstanding Graduate Award. He served as the principal investigator for a project supported by the National Natural Science Foundation of China, and received funding from the China Postdoctoral Science Foundation and the Guangdong Natural Science Foundation. His original research findings have been published in prestigious journals such as PNAS, Science China Life Sciences, Glia, and The FASEB Journal.
Representative publications：(#first author; *corresponding author)
1. Teng XY, Hu P*, Zhang CM, Zhang QX, Yang G, Zang YY, Liu ZX, Chen G*, Shi YS*. (2024) OPALIN is an LGI1 receptor promoting oligodendrocyte differentiation. PNAS, 121(32): e2403652121.
2. Teng XY, Hu P, Chen Y, Zang Y, Ye X, Ou J, Chen G*, Shi YS*. (2022) A novel Lgi1 mutation causes white matter abnormalities and impairs motor coordination in mice. FASEB J., 36(3): e22212.
3. Tu JJ#, Ye C#, Teng XY#, Zang YY, Sun XY, Chen S*, Chen J*, Shi YS*. (2025) Osmosensor TMEM63B facilitates insulin secretion in pancreatic β-cells. Sci China Life Sci., 68(6):1714-1726.
4. Liu M, Zhang Y, Teng XY#, Wang R, Liu Y, Hou J, Wang H*, Li YJ*, Wang Z*, Chen G*. (2025) Phosphatase PP2A is Required for CNS Myelination via Proteasome-Dependent Regulation of Sox10 Expression. Glia, 11. doi: 10.1002/glia.70082. Online ahead of print.
5. Tu JJ, Zang YY, Shi YS*, Teng XY*. (2024) The TMEM63B Channel Facilitates Intestinal Motility and Enhances Proliferation of Intestinal Stem Cells. Cells, 13(21): 1784.
6. Wang YY#, Wu D#, Zhan Y#, Li F, Zang YY, Teng XY, Zhang L, Duan GF, Wang H, Xu R, Chen G, Xu Y, Yang JJ*, Yu Y*, Shi YS*. (2025) Cation Channel TMEM63A Autonomously Facilitates Oligodendrocyte Differentiation at an Early Stage. Neurosci Bull., 41(4): 615-632.
7. Hu P#, Wu D#, Zang YY, Wang Y, Zhou YP, Qiao F, Teng XY, Chen J, Li QQ, Sun JH, Liu T, Feng HY, Zhou QG, Shi YS*, Xu Z*. (2022) A novel LGI1 mutation causing autosomal dominant lateral temporal lobe epilepsy confirmed by a precise knock-in mouse model. CNS Neurosci. Ther., 28(2): 237-246.
8. Bai Y#, Li MY#, Ma JB, Li JN, Teng XY, Chen YB, Yin JB, Huang J, Chen J, Zhang T, Qiu XT, Chen T, Li H, Wu SX, Peng YN, Li X*, Kou ZZ*, Li YQ*. (2020) Enkephalinergic circuit involved in nociceptive modulation in the spinal dorsal horn. Neuroscience, 429: 78-91.
9. Liao YH#, Wang J#, Wei YY, Zhang T, Zhang Y, Zuo ZF, Teng XY, Li YQ*. (2018) Histone deacetylase 2 is involved in µ‑opioid receptor suppression in the spinal dorsal horn in a rat model of chronic pancreatitis pain. Mol Med Rep., 17(2):2803-2810.
