Lu Xiaoyun
Master’s degree, Research Assistant
Email:luxiaoyun@@gdiist.cn
Personal Profile：
Graduated with a bachelor's degree in Biotechnology from Southern Medical University in 2022, and obtained a master's degree in Biology from Xiamen University in 2025. During the master's program, the primary research focused on changes in cellular plasticity during neural development and injury regeneration, exploring strategies to promote development and injury repair of white matter. Key involvement in the research project investigating the mechanism by which osteogenic Shn3 regulates oligodendrocyte differentiation and myelin regeneration.
Research Directions：
Mechanisms for white matter development and injury repair
Works：
1. Mei Wu, Man Li, Wei Liu, Minbiao Yan, Li Li, Weichao Ding, Ximing Nian, Wenxiu Dai, Di Sun, Yanqin Zhu, Qiuying Huang, Xiaoyun Lu, Zhiyu Cai, Fan Hong, Xuewen Li, Ling Zhang, Zhixiong Liu, Wei Mo, Xueqin Zhang and Liang Zhang. 2023. Nucleoporin Seh1 maintains Schwann cell homeostasis by regulating genome stability and necroptosis. Cell Reports.
2. Li Li, Daopeng Li, Di Sun, Xueqin Zhang, Wanying Lei, Mei Wu, Qiuying Huang, Ximing Nian, Wenxiu Dai, Xiaoyun Lu, Zhihao Zhou, Yanqin Zhu, Yunshan Xiao, Ling Zhang, Wei Mo, Zhixiong Liu and Liang Zhang. 2023. Nuclear import carrier Hikeshi cooperates with HSP70 to promote murine oligodendrocyte differentiation and CNS myelination. Developmental Cell.
3. Wenxiu Dai, Zhixiong Liu, Minbiao Yan, Ximing Nian, Fan Hong, Zhihao Zhou, Chaomeng Wang, Xing Fu, Xuewen Li, Mengyun Jiang, Yanqin Zhu, Qiuying Huang, Xiaoyun Lu, Lichao Hou, Ning Yan, Qin Wang, Jin Hu, Wei Mo, Xueqin Zhang and Liang Zhang. 2024. Nucleoporin Seh1 controls murine neocortical development via transcriptional repression of p21 in neural stem cells. Developmental Cell.
4. Wenxiu Dai, Ximing Nian, Zhihao Zhou, Ailian Du, Qi Liu, Shufang Jia, Yan Lu, Daopeng Li, Xiaoyun Lu, Yanqin Zhu, Qiuying Huang, Jiaquan Lu, Yunshan Xiao, Liangkai Zheng, Wanying Lei, Nengyin Sheng, Xiujuan Zang, Yanqiang Hou, Zilong Qiu, Ren Xu, Shuhua Xu, Xueqin Zhang and Liang Zhang. A neuronal Slit1-dependent program rescues oligodendrocyte differentiation and myelination under chronic hypoxic conditions. Cell Rep.
